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The research and design of intelligent autonomous tracing car measurement and control system

Wang Ling,Zhang Qiang and Li Xuemei

Strategic Study of CAE 2014, Volume 16, Issue 3,   Pages 92-98

Abstract:

Measurement and control system for intelligent car is one of the key technologies in the design ofstability of intelligent car.It introduces the whole architecture of intelligent autonomous tracing car measurement and control systemExcellent control algorithm plays a key role for intelligent car tracing accuracy and stability.The test results show that the intelligent car runs fast and smoothly，and can trace independently and

Keywords： intelligent car     measurement and control system     fuzzy PID control     double P control algorithm    

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The Largest Market for Civil Use of GPS ——Car Navigation System

Zhao Huiping

Strategic Study of CAE 2001, Volume 3, Issue 8,   Pages 64-69

Abstract:

According to the principle of positioning a new car navigation system of triple accuracy which consistsAt present, the most wide civilian application of the GPS is the car navigation system.It is the intelligent transporation system (ITS).

Keywords： GPS     car navigation     intelligent transportation system (ITS)    

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The Status and Problems in Developing Private Use Car for China

Guo Konghui

Strategic Study of CAE 2000, Volume 2, Issue 8,   Pages 25-30

Abstract:

Should China develop its private use car? What kind of passenger car should China develop?Should China develop its own passenger car industry?What is the way out for China´s passenger car industry?And how to develop Chinese passenger car industry?to solve the“auto disaster”problems is not to put more restrains on the use of private car

Keywords： Chinese auto industry     private use car     family use car     state and problems    

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CRISPR-Cas9 mediated LAG-3 disruption in CAR-T cells

Yongping Zhang, Xingying Zhang, Chen Cheng, Wei Mu, Xiaojuan Liu, Na Li, Xiaofei Wei, Xiang Liu, Changqing Xia, Haoyi Wang

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 554-562 doi: 10.1007/s11684-017-0543-6

Abstract:

T cells engineered with chimeric antigen receptor (CAR) have been successfully applied to treat advancedThe immunosuppressive nature of tumor microenvironment is considered one of the key factors limiting CAR-TWe successfully generated LAG-3 knockout T and CAR-T cells with high efficiency using LAG-3 knockout CAR-T cells displayed robust antigen-specific antitumor activity incell culture and in murine xenograft model, which is comparable to standard CAR-T cells.

Keywords： CAR-T     CRISPR-Cas9     LAG-3    

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Thermal response of steel framing members in open car park fires

Xia YAN; Marion CHARLIER; Thomas GERNAY

Frontiers of Structural and Civil Engineering 2022, Volume 16, Issue 9,   Pages 1071-1088 doi: 10.1007/s11709-022-0879-0

Abstract: For open car park structures, adopting a performance-based structural fire design is often justifiedthis design approach requires an accurate assessment of temperatures in structural members exposed to carThis paper describes a numerical study on the thermal exposure on steel framing members in open car parkResults show that temperatures in unprotected beams and columns are influenced by the section geometry, car

Keywords： open car park     localized fire     steel frame     numerical modeling     computational fluid dynamics    

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Electric Car Market Poised to Accelerate

Chris Palmer

Engineering 2021, Volume 7, Issue 2,   Pages 136-138 doi: 10.1016/j.eng.2020.12.009

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CAR T-cell immunotherapy: a powerful weapon for fighting hematological B-cell malignancies

Frontiers of Medicine 2021, Volume 15, Issue 6,   Pages 783-804 doi: 10.1007/s11684-021-0904-z

Abstract: Chimeric antigen receptor T-cell (CAR T) immunotherapy opens a new path for targeted therapy of hematologicalIn this review, through a representative case study, we summarize the current experience of CAR T-celleffects, the causative mechanisms of therapy resistance, and new strategies to improve the efficacy of CAR

Keywords： CAR T cells     hematological malignancies     review    

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The engineering and technology progress of CAR-CA

Zhao Qinping

Strategic Study of CAE 2009, Volume 11, Issue 10,   Pages 25-31

Abstract: To meet the requirement of the design and manufacture of commercial aircraft in China, CAR-CA(collaborativeThis paper introduced the engineering and technology progress of CAR-CA, including the system architecture

Keywords： augmented reality     collaboration     cockpit     design     maintenance    

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A fully solid-state cold thermal energy storage device for car seats using shape-memory alloys

Frontiers in Energy 2023, Volume 17, Issue 4,   Pages 504-515 doi: 10.1007/s11708-022-0855-3

Abstract: characteristics, the design of the shape-memory alloy based the cold thermal energy storage system for precooling cartemperature, elastocaloric materials, and the shape-memory alloy geometry scheme on the performance of car

Keywords： shape-memory alloy (SMA)     elastocaloric effect (eCE)     cooled seat     cold thermal energy storage    

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Programming CAR T cells to enhance anti-tumor efficacy through remodeling of the immune system

Xiaohui Wang, Zhiqiang Wu, Wei Qiu, Ping Chen, Xiang Xu, Weidong Han

Frontiers of Medicine 2020, Volume 14, Issue 6,   Pages 726-745 doi: 10.1007/s11684-020-0746-0

Abstract: Chimeric antigen receptor (CAR) T cells have been indicated effective in treating B cell acute lymphoblasticHowever, CAR T cells have achieved minimal success against solid malignancies because of the additionalIn this review, we focus on the recent advances in the engineering of CAR T cell therapies to restorethe immune response in solid malignancies, especially with CAR T cells acting as cellular carriers tothe anti-tumor outcomes of CAR T cell therapies in solid tumors.

Keywords： CAR T cells     immunoregulatory molecules     endogenous immune response     solid malignancies    

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CAR T cells redirected against tumor-specific antigen glycoforms: can low-sugar antigens guarantee a

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 322-338 doi: 10.1007/s11684-021-0901-2

Abstract: To date, six chimeric antigen receptor T cell (CAR-T) therapies have been permitted for the treatmentHowever, several clinical trials of solid tumor CAR-T therapies were prematurely terminated, or theyaberrantly glycosylated glycoforms of tumor-associated antigens can also minimize the off-tumor effects of CAR-Tdiscuss how underglycosylated antigens emerge and then detail the latest advances in the development of CAR-T-based

Keywords： cancer immunotherapy     chimeric antigen receptor     solid tumors     tumor-associated antigen     glycosylation     O-glycans     adoptive cell therapy    

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Developing Car Sharing to Promote an Automobile Power Strategy

Qiao Yingjun and Ji Xuehong

Strategic Study of CAE 2018, Volume 20, Issue 1,   Pages 120-126 doi: 10.15302/J-SSCAE-2018.01.017

Abstract: justify;">This study briefly introduces the present situation and the prospects of the development of carsharing in the current stage of automobile development, this study aims to explain the influence of carIn addition, this study proposes the idea that the government should put car sharing on the strategicautomobile power to create a favorable development environment and promote the rapid development of car

Keywords： car sharing     automobile power     problem     policy    

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exosomes induce initial activation by exosomal CD19 antigen but impair the function of CD19-specific CAR

Frontiers of Medicine doi: 10.1007/s11684-023-1010-1

Abstract: exosomes induce initial activation by exosomal CD19 antigen but impair the function of CD19-specific CAR

Keywords： exosomes induce activation     impair function CD19     exosomal CD19 antigen    

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Stability analysis of slopes with planar failure using variational calculus and numerical methods

Norly BELANDRIA, Roberto ÚCAR, Francisco M. LEÓN, Ferri HASSANI

Frontiers of Structural and Civil Engineering 2020, Volume 14, Issue 5,   Pages 1262-1273 doi: 10.1007/s11709-020-0657-9

Abstract: This study investigates the technique of variational calculus applied to estimate the slope stability considering the mechanism of planar failure. The critical plane failure surface should be determined because it theoretically indicates the most unfavorable plane to be considered when stabilizing a slope to rectify the instability generated by several statistically possible planes. This generates integrals that can be solved by numerical methods, such as the Newton Cotes and the finite differences methods. Additionally, a system of nonlinear equations is obtained and solved. The surface of the critical planar failure is determined by applying the condition of transversality in mobile boundaries, for which various examples are provided. The number of slices is varied in one of the examples, while the surface of the critical planar failure is determined in the others. Results are compared using analytical methods through axis rotations. All the results obtained by considering normal stress, safety factors, and critical planar failure are nearly the same; however, in this research, a study is carried out for “ ” number of slices using programming methods. Sub-routines are important because they can be applied in slopes with different geometry, surcharge, interstitial pressure, and pseudo-static load.

Keywords： slopes stability     planar failure     variational calculus     numerical methods    

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Chimeric Antigen Receptors and Regulatory T Cells: The Potential for HLA-Specific Immunosuppression in Transplantation Review

Sabrina Wright, Conor Hennessy, Joanna Hester, Fadi Issa

Engineering 2022, Volume 10, Issue 3,   Pages 30-43 doi: 10.1016/j.eng.2021.10.018

Abstract: to a predefined target by the inclusion of an antigen-specific binding region within the synthetic CARCAR expression within Tregs has been proposed as a therapy for autoimmune and inflammatory diseases,However, current research into CAR-Treg engineering is extremely limited, and there is uncertainty regardingThis review examines the rationale behind the development of CAR-Tregs, their significance for humantransplantation, potential designs, safety considerations, and comparisons of CAR-Tregs in transplantation

Keywords： Chimeric antigen receptors     T cell     Treg     Alloimmunity     Bioengineering     Transplant     Autoimmunity    

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Title Author Date Type Operation

The research and design of intelligent autonomous tracing car measurement and control system

Wang Ling,Zhang Qiang and Li Xuemei

Journal Article

The Largest Market for Civil Use of GPS ——Car Navigation System

Zhao Huiping

Journal Article

The Status and Problems in Developing Private Use Car for China

Guo Konghui

Journal Article

CRISPR-Cas9 mediated LAG-3 disruption in CAR-T cells

Yongping Zhang, Xingying Zhang, Chen Cheng, Wei Mu, Xiaojuan Liu, Na Li, Xiaofei Wei, Xiang Liu, Changqing Xia, Haoyi Wang

Journal Article

Thermal response of steel framing members in open car park fires

Xia YAN; Marion CHARLIER; Thomas GERNAY

Journal Article

Electric Car Market Poised to Accelerate

Chris Palmer

Journal Article

CAR T-cell immunotherapy: a powerful weapon for fighting hematological B-cell malignancies

Journal Article

The engineering and technology progress of CAR-CA

Zhao Qinping

Journal Article

A fully solid-state cold thermal energy storage device for car seats using shape-memory alloys

Journal Article

Programming CAR T cells to enhance anti-tumor efficacy through remodeling of the immune system

Xiaohui Wang, Zhiqiang Wu, Wei Qiu, Ping Chen, Xiang Xu, Weidong Han

Journal Article

CAR T cells redirected against tumor-specific antigen glycoforms: can low-sugar antigens guarantee a

Journal Article

Developing Car Sharing to Promote an Automobile Power Strategy

Qiao Yingjun and Ji Xuehong

Journal Article

exosomes induce initial activation by exosomal CD19 antigen but impair the function of CD19-specific CAR

Journal Article

Stability analysis of slopes with planar failure using variational calculus and numerical methods

Norly BELANDRIA, Roberto ÚCAR, Francisco M. LEÓN, Ferri HASSANI

Journal Article

Chimeric Antigen Receptors and Regulatory T Cells: The Potential for HLA-Specific Immunosuppression in Transplantation

Sabrina Wright, Conor Hennessy, Joanna Hester, Fadi Issa

Journal Article